Two PhD successes for Pharmacy
Mon, 22 Dec 2014 09:23:00 GMT
PhD students Adeola Adebisi and Muhammad Usman Ghori were recently awarded their PhDs following successful examinations.
Adeola worked on the development of drug delivery systems designed to target Helicobacter pylori, the bacteria associated with stomach ulcers and increased risk of gastric cancer. She developed particulate delivery systems that could remain in the stomach for extended periods, thus getting a higher concentration of antibiotic at the site of the infection. These particles can also be used for other applications requiring retention in the stomach.
During her studies, Adeola presented her findings at many conferences and published some of her findings in high impact journals and is continuing to prepare the rest for publication.
Adebisi, A. and Conway, B. (2011) ‘Gastroretentive microparticles for drug delivery applications’ Journal of Microencapsulation , 28 (8), pp. 689-708. ISSN 0265-2048
Adebisi, A. and Conway, B. (2014) ‘Preparation and characterisation of gastroretentive alginate beads for targeting H. pylori’ Journal of Microencapsulation , 31 (1), pp. 58-67. ISSN 0265-2048
Adebisi, A. and Conway, B. (2014) ‘Lectin-conjugated microspheres for eradication of Helicobacter pylori infection and interaction with mucus’ International Journal of Pharmaceutics , 470 (1-2), pp. 28-40. ISSN 0378-5173
Muhammad’s thesis is titled release kinetics, compaction and electrostatic properties of hydrophilic matrices. Polymers are often used to control the release rate of drugs from tablets to sustain their therapeutic effects within the body. In order to design successful formulations, it is essential to understand the processes that govern how these control the rate of release. Muhammad also has an excellent track record of presenting his results at conferences and publishing his findings in high quality journals.
Ghori, M., Ginting, G., Smith, A. and Conway, B. (2014) ‘Simultaneous quantification of drug release and erosion from hypromellose hydrophilic matrices’ International Journal of Pharmaceutics , 465 (1-2), pp. 405-412. ISSN 0378-5173
Ghori, M., Šupuk, E. and Conway, B. (2014) ‘Tribo-electric Charging and Adhesion of Cellulose Ethers and their Mixtures with Flurbiprofen’ European Journal of Pharmaceutical Sciences. ISSN 0928-0987
Ghori, M., Alba, K., Smith, A., Conway, B. and Kontogiorgos, V. (2014) ‘Okra Extracts In Pharmaceutical And Food Applications’ Food Hydrocolloids. ISSN 0268005X
Asare-Addo, K., Kaialy, W., Levina, M., Rajabi-Siahboomi, A., Ghori, M., Šupuk, E., Laity, P., Conway, B. and Nokhodchi, A. (2013) ‘The influence of agitation sequence and ionic strength on in vitro drug release from hypromellose (E4M and K4M) ER matrices--the use of the USP III apparatus.’ Colloids and Surfaces B: Biointerfaces , 104, pp. 54-60. ISSN 0927-7765
Šupuk, E., Ghori, M., Asare-Addo, K., Laity, P., Panchmatia, P. and Conway, B. (2013) ‘The influence of salt formation on electrostatic and compression properties of flurbiprofen salts’ International Journal of Pharmaceutics, 458 (1), pp. 118-127. ISSN 0378-5173
